M9281 Sigma 3-Methyladenine 100mg

اعتبار قیمت 96.10.30

 

لطفا پس از پایان اعتبار قیمت درخواست خود را در سبد خرید قرار دهید در کمتر از 30 دقیقه قیمت جدید اعلام میگردد (سبد خرید زیر عکس میباشد)


Properties

Related Categories Autophagy, Autophagy Inhibitors, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   PREMIUM
InChI Key   FSASIHFSFGAIJM-UHFFFAOYSA-N
mp   ~300 °C (dec.)(lit.)

Description

Packaging

100, 500 mg in poly bottle

Preparation Note

This product is soluble in DMF (10 mg/ml, may require gentle heating), yielding a clear, colorless solution. It is also soluble in water, 95% ethanol, or 1 N NaOH at 30 mg/ml with heating, but upon cooling, the product precipitates from solution. Solutions of 3-MA are best prepared fresh.

Application

3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is typically used at a concentration of 5 mM
فروشنده: آزمیران
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