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دستگاهای آزمایشگاهی
مواد شیمیایی
شیشه آلات
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جستجوهای مرتبط
Sildenafil citrate salt PZ0003-5MG Sigma
اعتبار قیمت 96.6.31
لطفا پس از پایان اعتبار قیمت درخواست خود را در سبد خرید قرار دهید در کمتر از 30 دقیقه قیمت جدید اعلام میگردد (سبد خرید زیر عکس میباشد)
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CAS Number 171599-83-0
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Empirical Formula (Hill Notation) C22H30N6O4S ·C6H8O7
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Molecular Weight 666.70
Properties
| Related Categories | Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, |
| InChI Key |
DEIYFTQMQPDXOT-UHFFFAOYSA |
| assay | ≥98% (HPLC) |
| form | white powder |
| solubility | DMSO: >20 mg/mL |
| originator | Pfizer |
| storage temp. | room temp |
Description
Other Notes
This compound was developed by Pfizer for Cyclic Nucleotides research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Biochem/physiol Actions
Sildenafil is a potent, selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5). Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension. NO activates guanylate cyclase, which results in increased levels of cGMP, producing smooth muscle relaxation. Sildenafil enhances the effect of NO by inhibiting PDE5, which is responsible for degradation of cGMP.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Safety Information
Symbol
Signal word
Warning
Hazard statements
Precautionary statements
RIDADR
NONH for all modes of transport
WGK Germany
3
فروشنده: آزمیران
گارانتی اصالت و سلامت کالا
پشتیبانی ۷ روز هفته ۲۴ ساعته
۸۵۹,۰۰۰ تومان
محصولات مرتبط
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