Anti-Acetylcholinesterase antibody [HR2] (ab2803)
Anti-Acetylcholinesterase antibody [HR2] (ab2803)

اعتبار قیمت 95.3.31

Overview

  • Product nameAnti-Acetylcholinesterase antibody [HR2]
    See all Acetylcholinesterase primary antibodies
  • Description
    Mouse monoclonal [HR2] to Acetylcholinesterase
  • SpecificityThis antibody does not detect butyrylcholinesterase (BChE).
  • Tested applicationsELISA, IHC-Fr, IP, Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rabbit, Guinea pig, Cow, Cat, Human, Macaque Monkey
    Predicted to work with: Non Human PrimatesDoes not react with: Rat, Amphibians
  • Immunogen

    Full length protein corresponding to Human Acetylcholinesterase. Purified Human cerebellar acetylcholinesterase.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration200 µl at 1 mg/ml 
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberHR2
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

ApplicationAbreviewsNotes
ELISA
Use at an assay dependent concentration.
IHC-Fr
1/50. Immunohistochemical staining of AChE in human brain samples results in staining of nerve fibers and terminals.
IP
Use at an assay dependent concentration.
Flow Cyt
Use 1µg for 106 cells.
ICC/IF
1/100 - 1/1000.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionTerminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
    • Tissue specificityIsoform H is highly expressed in erythrocytes.
    • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
    • Cellular localizationCell membrane; Cell junction > synapse. Secreted. Cell membrane and Nucleus. Only observed in apoptotic nuclei.


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