Hemoglobin human Sigma Aldrich H7379-1G

اعتبار قیمت 1400.1.1

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CAS Number 9008-02-0   MDL number MFCD00131282   eCl@ss 42030116

Properties

Related Categories         Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,

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form      lyophilized powder

impurities           HIV and hepatitis B antigen, tested negative

solubility             H2O: soluble 20 mg/mL

storage temp.  2-8°C

Gene Information           human ... HBA1(3039), HBA2(3040), HBB(3043), HBD(3045), HBE1(3046), HBG1(3047), HBG2(3048), HBQ1(3049), HBZ(3050)

Description

Biochem/physiol Actions

Oxygen transporter, NO scavenger

 

The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

 

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

 

Packaging

1, 5, 10 g in poly bottle

 

Application

Hemoglobin was used in the development of a rapid enzyme immunoassay for the detection of retinol-binding protein.[2] It was also used in the inhibition of human platelet reactivity by endothelium-derived relaxing factor.[1]

 

General description

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

 

Safety Information

RIDADR  NONH for all modes of transport WGK Germany  3

 


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